Successful Drug Discovery, Volume 1
David P Rotella editor János Fischer editor
Format:Hardback
Publisher:Wiley-VCH Verlag GmbH
Published:18th Mar '15
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The first volume of the book series "Successful Drug Discovery" is focusing on new drug discoveries during the last decade, from established drugs to recently introduced drugs of all kinds: small-molecule-, peptide-, and protein-based drugs.
The role of serendipity is analyzed in some very successful drugs where the research targets of the lead molecule and the drug are different. Phenotypic and target-based drug discovery approaches are discussed from the viewpoint of pioneer drugs and analogues.
This volume gives an excellent overview of insulin analogues including a discussion of the properties of rapid-acting and long-acting formulations of this important hormone.
The major part of the book is devoted to case histories of new drug discoveries described by their key inventors. Eight case histories range across many therapeutic fields.
The goal of this book series is to help the participants of the drug research community with a reference book series and to support teaching in medicinal chemistry with case histories and review articles of new drugs.
"In summary, this book provides a diverse set of insights into successful drug discovery cases and concepts. It is highly valuable both to support teaching and as a motivating read for medicinal chemists in academia and industry." (ChemMedChem, 1 October 2015)
"Because of the manner in which this book combines basic broad concepts (Section I), a detailed overview of an class of molecules (Section II), and narrowly focused case studies (Section III), it would be a valuable addition to the library of any group doing drug discovery and development." (Chemistry International 2016)
ISBN: 9783527336852
Dimensions: 252mm x 175mm x 18mm
Weight: 712g
256 pages