Transporters as Drug Targets
Helmut Buschmann editor Harald H Sitte editor Raimund Mannhold editor Gerd Folkers editor Gerhard F Ecker editor Rasmus P Clausen editor
Format:Hardback
Publisher:Wiley-VCH Verlag GmbH
Published:8th Feb '17
Currently unavailable, and unfortunately no date known when it will be back
As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets.
Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation.
With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease.
ISBN: 9783527333844
Dimensions: 249mm x 175mm x 23mm
Weight: 975g
354 pages