Analogue-based Drug Discovery
IUPAC author IUPAC editor János Fischer editor C Robin Ganellin editor
Format:Hardback
Publisher:Wiley-VCH Verlag GmbH
Published:3rd Feb '06
Currently unavailable, and unfortunately no date known when it will be back
The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds.
Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them.
The book includes a table of the most successful drug analogs as based on the IMS ranking and compares them in terms of chemical structure, mode of action and patentability.
"This book is eminently capable of educating both newcomers and experienced practitioners to the fields of medicinal chemistry and pharmacology, and it is highly recommended as an addition to the personal collection of the practicing drug designer and as a reference volume for institutional use as well."
Journal of Medicinal Chemistry
"Overall the book is of interest for medicinal chemists who already have a sound knowledge of aspects of analogue-based drug design." ChemMedChem
ISBN: 9783527312573
Dimensions: 243mm x 179mm x 38mm
Weight: 1162g
606 pages