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Alternatives for Dermal Toxicity Testing

Chantra Eskes editor Howard I Maibach editor Erwin van Vliet editor

Format:Paperback

Publisher:Springer International Publishing AG

Published:30th Aug '18

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Alternatives for Dermal Toxicity Testing cover

This book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scientific basis, validation status and regulatory acceptance, applications and limitations, available protocols, and potential role within testing strategies. In addition, perspectives from the test developer are presented, for example regarding critical steps in the protocol. The closing section addresses areas that may be of relevance for the future of dermal toxicity safety testing, including the validation and regulatory acceptance of integrated testing strategies, novel complex skin models, and high-throughput screening techniques.

ISBN: 9783319843780

Dimensions: unknown

Weight: unknown

592 pages

Softcover reprint of the original 1st ed. 2017