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Progress in the Chemistry of Organic Natural Products 115

Simon Gibbons editor A Douglas Kinghorn editor Heinz Falk editor Yoshinori Asakawa editor Ji-Kai Liu editor Verena M Dirsch editor

Format:Paperback

Publisher:Springer Nature Switzerland AG

Published:3rd Apr '22

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Progress in the Chemistry of Organic Natural Products 115 cover

This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.

ISBN: 9783030648558

Dimensions: unknown

Weight: unknown

203 pages

1st ed. 2021