Brain Glycogen Metabolism
Arne Schousboe editor Mauro DiNuzzo editor
Format:Paperback
Publisher:Springer Nature Switzerland AG
Published:20th Nov '20
Should be back in stock very soon
This paperback is available in another edition too:
- Hardback£149.99(9783030274795)
This book aims to provide a state-of-the-art summary of what is currently known about brain glycogen metabolism, detailing the recent advances in our understanding of why glycogen is so critical for normal brain function. The role of glycogen in cellular neurophysiology remains largely unclear and its specific contribution to the energy demand of brain cells is still elusive.Glycogen is the sole cerebral glucose reserve and is emerging as a fundamental component of brain energy metabolism. Pharmacological or genetic manipulation of glycogen metabolism in the brain impairs memory formation and increases susceptibility to epileptic seizures and cortical spreading depression. Glycogen is also directly implicated in abnormal neuronal excitability and mental retardation that characterize brain disorders like Lafora disease and Pompe disease.
ISBN: 9783030274825
Dimensions: unknown
Weight: unknown
443 pages
1st ed. 2019