Myelodysplastic Syndromes

Diagnosis - Prognosis - Therapy

Uwe Platzbecker editor Pierre Fenaux editor

Format:Paperback

Publisher:Springer Nature Switzerland AG

Published:22nd Dec '18

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Myelodysplastic Syndromes cover

This book reviews the standard diagnostic and therapeutic management of patients with myelodysplastic syndromes (MDS) and examines ongoing research developments in the field. The importance of appropriate prognostic stratification, taking into account recent advances in understanding of the molecular pathogenesis of MDS, is explained, and both established and novel treatment approaches are discussed in depth. The coverage includes, for example, the use of erythropoietic stimulating agents, iron chelation therapy, the immunomodulator lenalidomide, hypomethylating agents such as azacitidine, and allogeneic hematopoietic stem cell transplantation.

Myelodysplastic syndromes are heterogeneous and complex hematologic disorders ranging from indolent conditions to forms approaching the aggressiveness of acute myeloid leukemia. The diversity of MDS gives rise to challenges in diagnosis and clinical decision making, and the highly variable clinical course necessitates a risk-adapted treatment strategy and the application of disease-specific therapies. Hematologists, oncologists, and other interested clinicians will find this book to be an invaluable source of information on diagnostic and prognostic evaluation and treatment selection.

“This is an up‐to‐date review of the diagnostic and therapeutic management of patients with myelodysplastic syndromes (MDS). In light of the recent advances in this field, the book makes a laudable effort to highlight the importance of prognostic stratification and discusses in depth both standard therapeutic practices and novel approaches. … At barely 150 pages, this comprehensive yet succinct book is an excellent resource on MDS that is very informative, authoritative, and easy to read.” (Ravi Salgia, Doody's Book Reviews, December 14, 2018)

ISBN: 9783030083168

Dimensions: unknown

Weight: unknown

157 pages

Softcover reprint of the original 1st ed. 2018