Tangled Up

The only comprehensive guide to the history and science of Alzheimer’s disease.

This book will help you understand how the disease was discovered, why it is affecting our memory, what actually happens in the brain and how we can reduce our risk for Alzheimer’s disease.

With vivid examples, Professor Michael Hornberger takes you on a whistle-stop tour of every aspect of the most common form of dementia, from its origins to modern diagnosis and treatment.

You can discover scientifically proven Alzheimer’s disease prevention strategies and lifestyle changes.

You can understand why people with the disease are often ‘living in the last’ and get disoriented as to where they are.

And you can learn more about the rare forms of Alzheimer’s disease that are often mistaken for other conditions.

Written for the general public, this book deals with:

• What causes Alzheimer’s disease?
• Why Alzheimer’s often affects our memory first
• The role of genetics in raising and lowering risk for the disease
• What new treatments are emerging
• The chances you will inherit Alzheimer’s from your parents
• The practical steps you can take to reduce your future risk for Alzheimer’s disease

One in 14 people over 65 will get dementia and Alzheimer’s disease accounts for around 70% of all people with dementia.

Professor Michael Hornberger, a neuroscientist who has been researching people with Alzheimer’s for decades, has the key answers to help you and your family to understand the disease and reduce your risk for Alzheimer’s disease.

He starts by looking at the very first patient who was diagnosed with ‘Alzheimer’s’ disease - Auguste Deter. A German doctor, Alois Alzheimer, not only described her symptoms in meticulous detail but also reported after her death specific changes which are now the hallmark features of Alzheimer’s disease – so called tangles.

Tangled Up recounts Alzheimer’s intriguing interviews with Auguste Deter and the subsequent discovery of what was happening in the newly-named Alzheimer’s disease.

In essence, Alzheimer’s disease emerges when two proteins, amyloid and tau, build up in our brains. Once the proteins start accumulating, they start becoming toxic to the nerve cells which...

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