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Impact of Sleep and Sleep Disturbances on Obesity and Cancer

Susan Redline editor Nathan A Berger editor

Format:Hardback

Publisher:Springer-Verlag New York Inc.

Published:14th Dec '13

Should be back in stock very soon

Impact of Sleep and Sleep Disturbances on Obesity and Cancer cover

Sleep has recently been recognized as a critical determinant of energy balance regulating, restoration and repair of many of the physiologic and psychologic processes involved in modulating energy intake and utilization. In addition to having an impact on obesity, sleep abnormalities, both quantitative and qualitative, have now been shown to have significant effects on obesity associated comorbidities, including metabolic syndrome, premalignant lesions and cancer. Sleep problems and fatigue also constitute a significant challenge for the ever expanding group of cancer survivors. Moreover, circadian misalignment, such as that experienced by "shift workers" has been shown to be associated with an increased incidence of several malignancies including, breast, colorectal and prostate cancer, consistent with the increasing recognition of the role of clock genes in the metabolic processes. Of increasing concern is the accelerating incidence of sleep disorders in childhood, their association with childhood obesity and associated abnormalities of circulating cytokines, adipokines and metabolic factors, many of which are implicated as etiologic mediators of the connection between obesity and cancer.

Extensive studies have now been initiated to investigate the mechanisms by which disturbances in sleep duration, sleep continuity and sleep related breathing affect circadian rhythm, central and peripheral tissue oxygenation and metabolism, quality and quantity of dietary intake and circulating inflammatory cytokines and regulatory hormones. This volume aims to present the latest research on sleep, sleep disturbance and its correlation to obesity and cancer.

From the reviews:

“This book adopts a transdisciplinary approach and presents chapters authored by experts on sleep about the effect of sleep on obesity and cancer. … The book was written for students, researchers, and clinicians across all disciplines but specifically for those involved in sleep, energy balance, and cancer. … a worthwhile contribution to the field of sleep medicine. It provides a comprehensive review of the state-of-the-art studies on sleep, obesity, and cancer in order to provide information to researchers and clinicians.” (M. Isabel L. Crisostomo, Doody’s Book Reviews, June, 2

ISBN: 9781461495260

Dimensions: unknown

Weight: unknown

239 pages

2014 ed.