Fermentation and Biochemical Engineering Handbook

This handbook is a vital resource for fermentation engineers, covering processes, techniques, and modern advancements in biochemical engineering and fermentation applications.

The Fermentation and Biochemical Engineering Handbook serves as an essential resource for fermentation engineers involved in the commercial production of chemicals and pharmaceuticals. This comprehensive guide focuses on the operation, development, and design of manufacturing processes that incorporate fermentation, separation, and purification techniques. With contributions from industry leaders such as Merck, Eli Lilly, Amgen, and Bristol-Myers Squibb, the book highlights practical aspects of these processes, including data collection, scale-up parameters, equipment selection, and troubleshooting. It also offers insights into the various industry sectors that utilize fermentation techniques, encompassing chemicals, pharmaceuticals, food, and biofuels.

In its third edition, the Fermentation and Biochemical Engineering Handbook introduces new material that addresses contemporary topics such as recombinant cell fermentation, mammalian cell culture, and biorefinery operations. This ensures the book remains relevant to professionals around the globe. It uniquely illustrates the connections between synthetic processes for small molecules, like active ingredients and drugs, and the biotechnology involved in producing proteins, vaccines, hormones, and antibiotics.

Additionally, this major revision includes updated information on membrane pervaporation technologies for biofuels and nanofiltration, along with advancements in instrumentation, such as optical-based dissolved oxygen probes and real-time fermentation monitoring using wireless technology. Environmental considerations, including the application of new biotechnologies for waste treatment and renewable energy production from wastewaters, are also discussed, making this handbook a complete and up-to-date reference for scientists and engineers across various sectors.