Phenotypes and Genotypes
The Search for Influential Genes
David Ramsey author Florian Frommlet author Małgorzata Bogdan author
Format:Paperback
Publisher:Springer London Ltd
Published:20th Mar '19
Currently unavailable, and unfortunately no date known when it will be back
This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.
ISBN: 9781447173809
Dimensions: unknown
Weight: 454g
222 pages
Softcover reprint of the original 1st ed. 2016