Microarray Image Analysis

An Algorithmic Approach

Karl Fraser author Zidong Wang author Xiaohui Liu author

Format:Paperback

Publisher:Taylor & Francis Ltd

Published:14th Jun '17

Currently unavailable, and unfortunately no date known when it will be back

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Microarray Image Analysis cover

To harness the high-throughput potential of DNA microarray technology, it is crucial that the analysis stages of the process are decoupled from the requirements of operator assistance. Microarray Image Analysis: An Algorithmic Approach presents an automatic system for microarray image processing to make this decoupling a reality. The proposed system integrates and extends traditional analytical-based methods and custom-designed novel algorithms.

The book first explores a new technique that takes advantage of a multiview approach to image analysis and addresses the challenges of applying powerful traditional techniques, such as clustering, to full-scale microarray experiments. It then presents an effective feature identification approach, an innovative technique that renders highly detailed surface models, a new approach to subgrid detection, a novel technique for the background removal process, and a useful technique for removing "noise." The authors also develop an expectation–maximization (EM) algorithm for modeling gene regulatory networks from gene expression time series data. The final chapter describes the overall benefits of these techniques in the biological and computer sciences and reviews future research topics.

This book systematically brings together the fields of image processing, data analysis, and molecular biology to advance the state of the art in this important area. Although the text focuses on improving the processes involved in the analysis of microarray image data, the methods discussed can be applied to a broad range of medical and computer vision analysis areas.

Overall, this is a well-written book, and it should be useful for researchers and practitioners who work on microarray image analysis.
—Peihua Qiu, Technometrics, May 2012

ISBN: 9781138115156

Dimensions: unknown

Weight: 453g

336 pages