Sedimentation Velocity Analytical Ultracentrifugation

"Sedimentation Velocity Analytical Ultracentrifugation: Interacting Systems should be considered essential reading for those interested in the quantitative analysis of macromolecular interactions. The book lays out the fundamental theory of sedimentation for interacting systems, along with numerous examples that allow a visual and conceptual connection to the underlying math. This is followed with a discussion of approximate solutions of the Lamm equation for reacting systems, and analysis of the resultant sedimentation coefficient distributions. Of particular note is the chapter on practical considerations for experimental design and data interpretation, which should prove useful to experts and non-experts alike.
In light of the importance of interacting systems in both academic and industry settings, this book represents a timely and useful reference."
—David L Bain, Professor, University of Colorado Anschutz Medical Campus

"After laying down the fundamentals of analytical centrifugation in his first book, and the basis of sedimentation analysis of multicomponent systems in the second one, the third book in the series deals with the most crucial aspects, present in every practical case, arising from physical and chemical interactions between the different species in the sample.
Dr. Schuck presents a detailed description of the nature of the interactions, their influence in the sedimentation patterns, and the ways to account for them in the analysis of experimental data. The author considers, on the one hand, physical intramolecular interactions, showing how they must be properly considered when one looks for structural information of the individual species. And, on the other hand, the book dwells amply in the most significant case of chemically reacting systems. The homo- or hetero-association of biomacromolecules is an aspect of extraordinary importance in many topics in life sciences, from signalling processes in s