Predictive ADMET
Integrated Approaches in Drug Discovery and Development
Laszlo Urban author Jianling Wang author
Format:Hardback
Publisher:John Wiley & Sons Inc
Published:30th May '14
Currently unavailable, and unfortunately no date known when it will be back
This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so that pharmaceutical scientists can diagnose ADMET problems and present appropriate recommendations to move drug discovery programs forward.
The book introduces the current clinical practice for drug discovery and development along with the impact on early risk assessment; consolidates the tools and models to intelligently integrate existing in silico, in vitro and in vivo ADMET data; and demonstrates successful cases and lessons learned from real drug discovery and development. In short, it is a book aimed to provide a practical road map for drug discovery and development scientists to generate efficacious and safe drugs for unmet medical needs.
“In conclusion, this volume fulfills its promise of being a very useful tool for guidance and diagnosis on ADMET matters, and I would recommend it to any scientist in the field.” (ChemMedChem, 1 June 2015)
ISBN: 9781118299920
Dimensions: 244mm x 164mm x 39mm
Weight: 989g
624 pages