Handbook of Generalized Pairwise Comparisons
Methods for Patient-Centric Analysis
Geert Molenberghs editor Marc Buyse editor Everardo D Saad editor Johan Verbeeck editor Mickaël De Backer editor Vaiva Deltuvaite-Thomas editor
Format:Paperback
Publisher:Taylor & Francis Ltd
Publishing:31st Mar '25
£57.99
This title is due to be published on 31st March, and will be despatched as soon as possible.
This paperback is available in another edition too:
- Hardback£180.00(9781032488035)
In today's healthcare landscape, there is a pressing need for quantitative methodologies that include the patients' perspective in any treatment decision.
Handbook of Generalized Pairwise Comparisons: Methods for Patient-Centric Analysis provides a comprehensive overview of an innovative and powerful statistical methodology that generalizes the traditional Wilcoxon-Mann-Whitney test by extending it to any number of outcomes of any type, and including thresholds of clinical relevance into a single, multidimensional evaluation.
The book covers the statistical foundations of generalized pairwise comparisons (GPC), applications in various disease areas, implications for regulatory approvals and benefit-risk analyses, and considerations for patient-centricity in clinical research. With contributions from leading experts in the field, this book stands as an essential resource for a more holistic and patient-centric assessment of treatment effects.
“This book stands as a guiding beacon for developers, researchers, and regulators, sparking the evolution of fit-for-dossier trials into agile studies tailored for informed decisions.” Francesco Pignatti, Head of the Office of Oncology and Haematology, European Medicines Agency, Amsterdam, the Netherlands.
“The editors of this book and the chapter authors are to be commended for consolidating the considerable advances in GPC statistical methods into a single comprehensive resource that should serve as a standard for many years to come.” Gene Pennello, Mathematical Statistician, US Food and Drug Administration, Bethesda, MD.
ISBN: 9781032488059
Dimensions: unknown
Weight: unknown
600 pages