Oxidative Stress and Cardiac Failure
Valentin Fuster editor Marrick Kukin editor
Format:Hardback
Publisher:John Wiley and Sons Ltd
Published:29th Nov '02
Currently unavailable, and unfortunately no date known when it will be back
Far from being a direct complication of primary damage to heart muscle, it is now recognised that the pathogenesis of heart failure may rely on a combination of neurohormonal, cellular and molecular factors. An overwhelming number of systems appear to be activated in heart failure and contribute in some way towards structural remodelling.
Comprising a comprehensive evaluation of the experimental and clinical data relating oxidative stress and heart failure, this text proposes that oxidative stress may be the common pathway for muscle dysfunction, cellular growth and remodelling, and mytocyte death. Acknowledged experts in the field here present a persuasive argument for raising the profile of oxidative stress as an important, perhaps critical contributor to the adverse consequences of heart failure. This volume should serve as a rich source of supportive data for clinicians and investigators interested in the pathophysiology and treatment of heart failure, and as a platform on which to base further research.
"The authors, experts in the field, describe the methods and results of their studies conducted in their own laboratory. Nevertheless, the authors manage to keep the text focused and quite comprehensible for the general clinician...
"This book provides a comprehensive overview of the heart failure syndrome and the evidence of the role of oxidative stress in its development...
"This book can be useful for clinicians to further their understanding of the pathogenesis of heart failure and how the different therapeutic pathways may improve mortality and morbidity. Furthermore, for those who are currently pursuing research in this field, the book serves as an excellent reference guide in addition to being a source of ideas and encouragement."
Jose C Mendez, MD (Loyola University Stritch School of Medicine)
Doody's Review Service
"This book provides a comprehensive overview of the heart failure syndrome and the evidence of the role of oxidative stress in its development. The tables and illustrations in the book help to deepen the understanding of the text. This book can be useful for clinicians to further their understanding of the pathogenesis of heart failure and how the different therapeutic pathways may improve mortality and morbidity. Furthermore, for those who are currently pursuing research in this field, the book serves as an excellent reference guide in addition to being a source of ideas and encouragement." (Jose C Mendez, MD, @Doody's Review Service)
ISBN: 9780879937096
Dimensions: 236mm x 163mm x 24mm
Weight: 680g
320 pages