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Chronic Lymphoid Leukemias

Bruce D Cheson author

Format:Hardback

Publisher:Taylor & Francis Inc

Published:25th Apr '01

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Chronic Lymphoid Leukemias cover

Written by over 50 internationally distinguished experts, 30 more than the first edition, and contains nine new chapters!

Continuing in the esteemed tradition and heralded success of the first edition, Chronic Lymphoid Leukemias, Second Edition offers a full overview of chronic lymphocytic leukemia (CLL) from multiple perspectives-covering all major developments since the previous edition was published eight years ago.

Chronicling the complete history and variations of CLL-type leukemia, the Second Edition

  • reviews the origin, nature, and molecular differences between B-CLL and T-CLL/PLL leukemias
  • analyzes core constituents of apoptosis and causes for dysregulation of programmed cell death (PCD) in B-CLL
  • examines recent research on the role cytokines and regulatory molecules may play in cross-cell communication
  • profiles commonly used vectors for somatic gene therapy, as well as the latest advances in genetic engineering and vector design and production
  • utilizes up-to-the-minute techniques such as fluorescence in-situ hybridization (FISH) and comparative genomic hybridization (CGH) to detect genetic abnormalities and aberrations
  • explores current measures of supportive care with splenectomy, cytokine proteins, and intravenous immunoglobulin applications
  • identifies how to manage infectious and psychiatric complications in patients with CLL
  • and much more!
    Provides contemporary results on the efficacy of nucleoside analog combinations such as ara-C with fludarabine and cladribine and on the emerging nucleosides nelarabine and clofarabine!

    Copiously supplemented with over 2500 literature references-1000 more than the first edition-Chronic Lymphoid Leukemias, Second Edition fulfills the reference needs of oncologists, hematologists, immunologists, pathologists, infectious disease specialists, internists, molecular biologists, and medical school students in these disciplines.<

    • "
    Praise for the first edition…

    An informative, up-to-date, well-referenced, and user-friendly text.
    With an illustrious cadre of authors, Cheson has crafted together state-of-the-art reviews...
    …a valuable addition to reference libraries…this compendium meets the need for an excellent reference text on CLL."-Hematologic Pathology
    "…[an] important book.
    …well written and edited….the editor deserves praise for…fostering a general sense of continuity."-The New England Journal of Medicine
    "…of great value to hematologists and oncologists….readers will learn a lot about the recent progress in CLL."-International Journal of Hematology
    "…a valuable contribution in bringing together disparate aspects of biology and clinical management of CLL….a useful compendium."-Australian Cancer Society

    "…should be ready by everyone taking care of pediatric patients with chronic lymphocytic leukemia (CLL)…up-to-date….an excellent, comprehensive review of the current treatment modalities….
    …the best review of CLL and related diseases currently available.
    "-Annals of Oncology

    ISBN: 9780824705435

    Dimensions: unknown

    Weight: 1315g

    664 pages

    2nd edition