Antipsychotic Trials in Schizophrenia

This book presents the results of the landmark CATIE study, a long and comprehensive study of schizophrenia.

CATIE was the largest, longest and most comprehensive study of schizophrenia to date. This book presents the definitive archival results of this landmark study, with chapters focused on specific outcomes, setting the findings in a wider context. Essential reading for psychiatrists, psychiatric researchers, mental health policy makers and pharmaceutical companies.Antipsychotic medications are a key treatment for schizophrenia and sales of antipsychotic drugs approach $20 billion per year, with fierce marketing between the makers of the drugs. The U.S. National Institute of Mental Health sponsored the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project to provide independent information about the comparative effectiveness of medications. CATIE was the largest, longest and most comprehensive study of schizophrenia to date. Conducted under rigorous double-blind conditions, Antipsychotic Trials in Schizophrenia presents the definitive archival results of this landmark study. The core of the book consists of chapters focused on specific outcomes that set the CATIE findings in a wider context. Also included are chapters on the design, statistical analyses and implications for researchers, clinicians and policy makers. Psychiatrists, psychiatric researchers, mental health policy makers and those working in pharmaceutical companies will all find this to be essential reading.