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Bacterial Cell-to-Cell Communication

Role in Virulence and Pathogenesis

Donald R Demuth editor Richard Lamont editor

Format:Hardback

Publisher:Cambridge University Press

Published:23rd Feb '06

Currently unavailable, and unfortunately no date known when it will be back

Bacterial Cell-to-Cell Communication cover

Descibes latest developments in bacterial communication and the role of these mechanisms in disease.

Written by leading experts, this book summarises recent advances in the field of bacterial communication to allow students and researchers to keep abreast of the latest developments. The book describes how bacteria communicate and the relevance of these communication pathways to the disease process.Many bacterial diseases are caused by organisms growing together as communities or biofilms. These microorganisms have the capacity to coordinately regulate specific sets of genes by sensing and communicating amongst themselves utilizing a variety of signals. This book examines the mechanisms of quorum sensing and cell-to-cell communication in bacteria and the roles that these processes play in regulating virulence, bacterial interactions with host tissues, and microbial development. Recent studies suggest that microbial cell-to-cell communication plays an important role in the pathogenesis of a variety of disease processes. Furthermore, some bacterial signal molecules may possess immunomodulatory activity. Thus, understanding the mechanisms and outcomes of bacterial cell-to-cell communication has important implications for appreciating host-pathogen interactions and ultimately may provide new targets for antimicrobial therapies that block or interfere with these communication networks.

'This is an interesting book covering intercellular chemical signalling in diverse bacteria … The likely target audience for this book would be senior undergraduates and researchers for whom it would give a good contemporary introduction to signalling in different bacteria.' George Salmond, University of Cambridge

ISBN: 9780521846387

Dimensions: 234mm x 157mm x 21mm

Weight: 663g

330 pages