Calcium, Oxygen Radicals and Cellular Damage

C J Duncan editor

Format:Paperback

Publisher:Cambridge University Press

Published:28th Jan '08

Currently unavailable, and unfortunately no date known when it will be back

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Calcium, Oxygen Radicals and Cellular Damage cover

A description of the biochemical processes that occur during cellular damage of specific organs; for example, what happens to the cells during heart attacks, strokes and muscular dystrophy.

The cellular events underlying rapid cellular damage in different organs are potentially of great medical importance, for example muscular dystrophy, liver damage and the preservation of kidneys for transplantation. Many hypotheses exist for the biochemical pathways involved in these damage processes. The roles of calcium and active oxygen metabolites are of particular interest. There is considerable literature on both these triggering agents and good evidence for their involvement in the genesis of damage, although little agreement on their precise roles. This volume records the proceedings of a meeting held by the Society for Experimental Biology that attempted to determine whether there are common mechanisms of cellular damage and to explore the ways in which calcium and oxygen radicals may interact to generate damage. The questions addressed, in particular, are whether there are any common biochemical pathways, and the specific and possibly interacting roles of calcium and active oxygen metabolites.

"...I could hardly put this book down, I constantly refer to it and my own research has already benefitted from the knowledge and opinion contained within....I am sure you will find it a very useful reference text too; and also a very good read." J. Lunec, BSCB Newsletter
"...a timely reminder of the much-needed research effort in this area." John M. C. Gutteridge, Quarterly Review of Biology

ISBN: 9780521057615

Dimensions: 229mm x 154mm x 15mm

Weight: 396g

240 pages