Muscle Disease

This comprehensive resource clarifies the pathology and genetics of muscle diseases, aiding diagnosis and management. It features contributions from over 60 experts, organized around the motor unit concept for easy navigation.

Muscle Disease is a comprehensive resource designed to enhance the understanding of the pathology and genetics of muscle disorders for pathologists, clinicians, geneticists, and researchers. The book is structured around the concept of the motor unit, presenting the latest insights into muscle diseases and their implications for identifying potential new treatments. With contributions from over 60 international experts, it reflects the significant advancements in the field over recent years.

The organization of the book allows for a clear exploration of complex principles related to muscle disorders. It focuses on inherited conditions, specifically examining the ultrastructure and organelles within muscle fibers. This logical arrangement enables the reader to navigate the diverse range of muscle diseases, from neurogenic and inflammatory disorders to those associated with single-gene defects. Disorders affecting specific organelles or metabolic processes are grouped together, facilitating a better understanding of conditions related to the sarcolemma, mitochondria, myofibrils, and metabolic pathways.

Throughout the text, clinical aspects and classifications of muscle diseases are emphasized. Each chapter begins with a clinical overview and includes dedicated clinical sections, ensuring that readers can easily access pertinent information. The standard format of each chapter aids in navigating the intricate variety of muscle disorders, making Muscle Disease an invaluable resource for professionals engaged in the diagnosis, research, treatment, and management of patients with muscle diseases.