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Applications of Transition Metal Catalysis in Drug Discovery and Development

An Industrial Perspective

Matthew L Crawley editor Barry M Trost editor

Format:Hardback

Publisher:John Wiley & Sons Inc

Published:26th Jul '12

Currently unavailable, and unfortunately no date known when it will be back

Applications of Transition Metal Catalysis in Drug Discovery and Development cover

This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs.  The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development – it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field.

“The book will be particularly appreciated by young scientists, especially those aspiring to a future in the pharmaceutical industry, because it shows what kind of problems they will be asked to solve once they start their industrial career.”  (ChemMedChem, 1 March 2013)

“All chapters are well-written and comprehensive with lots of examples from OPR and D.  The book is highly recommended to all process chemists.”  (Organic Process Research & Development Journal, 1 November 2012)

ISBN: 9780470631324

Dimensions: 236mm x 163mm x 25mm

Weight: 658g

384 pages