The Role of Glia in Neurotoxicity

This book offers a thorough examination of glial cells and their critical role in neurotoxicity, making it a unique resource in the field.

The second edition of The Role of Glia in Neurotoxicity presents cutting-edge research on glial cell function, derived from advancements in imaging and molecular biology. This comprehensive text delves into various aspects of glial cells, including their morphology, physiology, pharmacology, and biochemistry. It also examines the role of glia in the pathophysiology of neurological diseases, providing a detailed analysis of glial-neuronal interactions throughout different life stages, from development to senescence. Specific examples of glial-mediated neurotoxicity are highlighted, alongside discussions of miscellaneous topics such as signaling and edema.

In this updated edition, readers will discover new insights into neuronal-glia metabolic interactions and glutamate homeostasis, as well as the role of zinc transporters in glial cells. The text addresses unique susceptibilities of astrocytes to energy deprivation and mitochondrial dysfunction, alongside the implications of astrocytes in MPTP neurotoxicity and food toxins. These advancements reflect the growing recognition of the critical role glia play in neurotoxicology, filling a significant gap in existing literature.

The Role of Glia in Neurotoxicity is authored by leading experts in the field, ensuring that it remains the only dedicated resource for exploring the intersection of glial biology and neurotoxicology. With its broader scope compared to the first edition, this text is an essential reference for researchers and practitioners seeking to understand glial involvement in neurological disorders.