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Herbal Treatment of Major Depression

Scientific Basis and Practical Use

Scott D Mendelson author

Format:Hardback

Publisher:Taylor & Francis Ltd

Published:30th Oct '19

Currently unavailable, and unfortunately no date known when it will be back

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Herbal Treatment of Major Depression cover

This unique volume presents new understandings of the neurochemical nature of major depression, and how herbs and their constituent flavonoids and terpenes appear to address some of the mechanisms now thought to be involved. It explores how recent studies of the rapid antidepressant effects of ketamine inform neuroscientists about deep intracellular mechanisms of antidepressant action that have little to do with simple enhancement of monoaminergic activity. These mechanisms include actions on PI3K, Akt, mTOR, GSK3, BDNF, and other intracellular pathways. New theories of the pathophysiology underlying major depression, such as oxidative damage, inflammation, stress and insulin resistance are then explored.

Key Features:

  • Focuses on oxidative damage, inflammation, and metabolic syndrome.
  • Explains that a significant percentage of people treated for major depression obtain little if any relief from standard antidepressant medications.
  • These facts lead to discussion of herbs that can be used to treat major depression, as well as consideration of the scientific basis for how these herbs act.
  • The antidepressant properties of 66 herbs are discussed, along with dosing and safety information.
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Scott Mendelson, MD, PhD, has written a landmark volume in the Clinical Pharmacognosy series on Botanical Medicines for CRC Press. Why is this a landmark book? It thoughtfully reviews theories of the mechanisms of activity for antidepressants, including ketamine, and lays out the evidence for herbal activity through those mechanisms.

. . . .

I highly recommend this book for psychiatrists and other health professionals treating depression. Furthermore, phytopharmaceutical researchers interested in developing new treatments will find valuable ideas to pursue

Richard P. Brown, Review of Herbal Treatment of Major Depression: Scientific Basis and Practical Use, Psychiatric Times, 20th January 2020

Full Review: www.psychiatrictimes.com/film-and-book-reviews/herbal-treatment-major-depression-scientific-basis-and-practical-use

ISBN: 9780367375324

Dimensions: unknown

Weight: 1640g

420 pages