Insulin
Deficiency, Excess and Resistance in Human Disease
Format:Paperback
Publisher:Elsevier Science & Technology
Published:22nd Jan '24
Currently unavailable, and unfortunately no date known when it will be back
Insulin: Deficiency, Excess and Resistance in Human Disease provides an overview of the role of insulin in the pathogenesis of prevalent non-communicable diseases such as obesity, type 2 diabetes, cardiovascular disease, and cancer, along with a comprehensive review of insulin replacement therapies and novel cardioprotective and insulin-sensitizing drugs. Notable advances in precision diagnosis and therapy for single gene subtypes of diabetes in recent years are also discussed. The discovery of insulin and its lifesaving introduction into clinical practice is one of the most celebrated accomplishments of medical science. However, despite decades of progress and major technical advances, the goal of providing insulin replacement therapy that truly mimics normal physiology remains elusive.
*5 stars* "...comprehensively covers the topic by first addressing the normal physiology of insulin, including biosynthesis, physiologic actions, and nonclassic actions. [Also] cover the role of insulin in diseases in states of excess and resistance, as well as treatment approaches.... [U]seful to all levels of learners including medical students, residents, fellows, and attending physicians as it provides an overview of insulin that would be beneficial to any level of medical learner.... [D]oes an excellent job of first giving a very in-depth overview of the basic biosynthesis and physiology of insulin - which provides the reader with the necessary basis to move forward into the pathophysiology chapters.... [U]ses frequent historical contexts and origin stories which were a nice way to engage by providing context.... [A]n excellent reference, especially for use when coming across patients with gray-area or complex diabetes." --©Doody’s Review Service, 2024, Prathayini Subarajan, DO (Loyola University Stritch School of Medicine)
ISBN: 9780323917070
Dimensions: unknown
Weight: 900g
444 pages