The Chemistry of Microbiomes

Proceedings of a Seminar Series

Division on Earth and Life Studies author Board on Chemical Sciences and Technology author Chemical Sciences Roundtable author National Academies of Sciences, Engineering, and Medicine author

Format:Paperback

Publisher:National Academies Press

Published:19th Aug '17

Currently unavailable, and unfortunately no date known when it will be back

The Chemistry of Microbiomes cover

The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication.

The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystems—earth, marine, and human—and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.

Table of Contents
  • Front Matter
  • 1 Introduction
  • 2 Illuminating the Microbial Dark Matter Beneath Your Feet: Microbial Catalysis in the Terrestrial Subsurface - Kelly C. Wrighton, Rebecca A. Daly, and Michael J. Wilkins
  • 3 Life in High-Temperature Environments: Modern-Day Analogs of Early Earth Still Relevant Today - William P. Inskeep
  • 4 Advancing Our Understanding of the Chemistry of Soil Microbiomes - Trent R. Northen, Zheyun Zhang, Jian Gao, Tami Swenson, and Yasuo Yoshikuni
  • 5 Envisioning a Chemical Metaproteomics Capability for Biochemical Research and Diagnosis of Global Ocean Microbiomes - Mak A. Saito, Chip Breier, Mike Jakuba, Matthew McIlvin, and Dawn Moran
  • 6 Chemical Ecology: The Language of Microbiomes - Mark E. Hay, Deanna S. Beatty, and Frank J. Stewart
  • 7 Organic Nutrient Chemistry and the Marine Microbiome - Daniel J. Repeta and Rene M. Boiteau
  • 8 Digitizing the Chemistry Associated with Microbes: Importance, Current Status, and Opportunities - Pieter C. Dorrestein
  • 9 Deciphering the Chemistry of the Human Gut Microbiome - Emily P. Balskus
  • 10 Engineering the Microbiome for Human Health Applications - Timothy K. Lu, Mark Mimee, Robert J. Citorik, and Karen Pepper
  • 11 Talking with Molecules: Marine Bacteria and Microalgae - Mohammad R. Seyedsayamdost
  • 12 Genome-Scale Metabolic Modeling...

ISBN: 9780309458368

Dimensions: unknown

Weight: unknown

132 pages