Saving Women's Lives

The outlook for women with breast cancer has improved in recent years. Due to the combination of improved treatments and the benefits of mammography screening, breast cancer mortality has decreased steadily since 1989. Yet breast cancer remains a major problem, second only to lung cancer as a leading cause of death from cancer for women. To date, no means to prevent breast cancer has been discovered and experience has shown that treatments are most effective when a cancer is detected early, before it has spread to other tissues. These two facts suggest that the most effective way to continue reducing the death toll from breast cancer is improved early detection and diagnosis.

Building on the 2001 report Mammography and Beyond, this new book not only examines ways to improve implementation and use of new and current breast cancer detection technologies but also evaluates the need to develop tools that identify women who would benefit most from early detection screening. Saving Women's Lives: Strategies for Improving Breast Cancer Detection and Diagnosis encourages more research that integrates the development, validation, and analysis of the types of technologies in clinical practice that promote improved risk identification techniques. In this way, methods and technologies that improve detection and diagnosis can be more effectively developed and implemented.

Table of Contents

• Front Matter
• Executive Summary
• 1 Introduction
• 2 Benefits and Limitations of Mammography
• 3 Improving Breast Cancer Screening Services
• 4 Understanding Breast Cancer Risk
• 5 Biologically-Based Technologies
• 6 The Necessary Environment for Research and Development
• 7 Translating New Technologies into Improved Patient Outcomes
• 8 Recommendations
• Appendix A: Breast Cancer Technology Overview
• Appendix B: Workshop Agendas
• Appendix C: ROC Analysis: Key Statistical Tool for Evaluating Detection Technologies
• Appendix D: Common Weaknesses in Study Designs
• Glossary
• Index
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