Duchenne Muscular Dystrophy
Alan E H Emery author Francesco Muntoni author Rosaline C M Quinlivan author
Format:Hardback
Publisher:Oxford University Press
Published:19th Feb '15
Currently unavailable, and unfortunately no date known when it will be back
Duchenne Muscular Dystrophy, an inherited and progressive muscle wasting disease, is one of the most common single gene disorders found in the developed world. In this fourth edition of the classic monograph on the topic, Alan Emery and Francesco Muntoni are joined by Rosaline Quinlivan, Consultant in Neuromuscular Disorders, to provide a thorough update on all aspects of the disorder. Recent understanding of the nature of the genetic defect responsible for Duchenne Muscular Dystrophy and isolation of the protein dystrophin has led to the development of new theories for the disease's pathogenesis. This new edition incorporates these advances from the field of molecular biology, and describes the resultant opportunities for screening, prenatal diagnosis, genetic counselling and from recent pioneering work with anti-sense oligonucleotides, the possibility of effective RNA therapy. Although there is still no cure for the disorder, there have been significant developments concerning the gene basis, publication of standards of care guidelines, and improvements in management leading to significantly longer survival, particularly with cardio-pulmonary care. The authors also investigate other forms of pharmacological, cellular and gene therapies. Duchenne Muscular Dystrophy will be essential reading not only for scientists and clinicians, but will also appeal to therapists and other professionals involved in the care of patients with muscular dystrophy.
A highly specialized book like this requires expertise and a unique perspective, and there are no comparable books. The authors have been able to present the information concisely and simply, resulting in an easy to read book. * Doody's Notes *
I can visualise this book being used by a wide variety of professionals including medical students, junior doctors, general physicians, neuromuscular physicians and physical therapists. I would have no hesitation in adding this book to my own departmental library as a reference book for DMD. * Neuromuscular Disorders Journal *
ISBN: 9780199681488
Dimensions: 241mm x 162mm x 21mm
Weight: 690g
320 pages
4th Revised edition