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Lymphocytes

A Practical Approach

Andrew McMichael editor Sarah L Rowland-Jones editor

Format:Paperback

Publisher:Oxford University Press

Published:16th Dec '99

Currently unavailable, and unfortunately no date known when it will be back

Lymphocytes cover

Cellular immunology is a rapidly moving field in which recent advances have made significant contributions to our understanding of the immune response to infection and malignancy. These in turn, have given rise to new therapeutic opportunities in areas such as vaccines and immunotheraphy. Many investigators have been discourages by the complicated protocols involved in cellular immunological studies, as illustrated, by the meticulous care required for the generation of antigen-specific T-cells. Lymphocytes: A Practical Approach (second edition) contains straight-forward protocols for well- established procedures in the study of lymphocytes including preparation and identification of lymphocytes, immortalization, cell and organ culture, and quantification assays. It also covers the recent technological advances which have revolutionised the field, such as the use of the Interferon-gamma ELISpot assay and peptide-HLA tetrameric assays to quantify antigen-specifidc T-cells directly from peripheral blood, without the need for in vitro culture, and molecular methods for accurate HLA typing.

"... the book contains extremly useful practical advice for studying lymphocytes in the laboratory..." Parasitology Today

ISBN: 9780199638161

Dimensions: 234mm x 157mm x 21mm

Weight: 649g

376 pages

2nd Revised edition