PAKs, RAC/CDC42 (p21)-activated Kinases

Towards the Cure of Cancer and Other PAK-dependent Diseases

Hiroshi Maruta editor

Format:Hardback

Publisher:Elsevier Science Publishing Co Inc

Published:1st Feb '13

Currently unavailable, and unfortunately no date known when it will be back

PAKs, RAC/CDC42 (p21)-activated Kinases cover

Covers a variety of basic and clinical PAK research ranging from laboratory benches to hospital beds. This book consists of 9 chapters which deal with different aspects of this kinase. It describes a number of PAK blockers which would be useful for the therapy of these PAK-dependent diseases, and some of them are available on the market.This book covers a variety of cutting-edge basic and clinical PAK research ranging from laboratory benches to hospital beds. The goal of this book is to inspire not only biomedical research scientists and university students, but also a variety of patients who suffer from PAK-dependent diseases and clinical doctors who try to cure or delay these PAK-dependent diseases.This book consists of 9 chapters which deal with different aspects of this kinase. These chapters are written by more than two dozen world-leading PAK experts. Each of these will provide updated biomedical information as well as future insight to a wide range of readers who are interested in this unique kinase and both its pathological and physiological roles as well as its functional evolution from its ancestral origins.

"Here neurologists and other biomedical researchers explain in some detail how PAKs — particularly the oncogenic kinases PAK1 and PAK4 and their blockers — may control various aspects of life and health, and how mammalian PAKs have functionally evolved from their ancestral origins in unicellular organisms such as yeast and amoebas through a series of mutations over millions of years." --Reference and Research Book News, August 2013

ISBN: 9780124071988

Dimensions: unknown

Weight: 390g

276 pages