Phosphodiesterase Inhibitors

Clive Page editor Christian Schudt editor Gordon Dent editor Klaus F Rabe editor

Format:Hardback

Publisher:Elsevier Science Publishing Co Inc

Published:16th Aug '96

Currently unavailable, and unfortunately no date known when it will be back

Phosphodiesterase Inhibitors cover

Key Features * Utilizes actual testing and research of new PDE inhibitors * Valuable for researchers and students alike

Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been in use since 1958. A variety of these inhibitors are under test as potential anti-inflammatory drugs. This book summarizes the developments, as well as giving a comprehensive description of the compounds available.Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of these new inhibitors are under test as potential anti-inflammatory drugs. During the past five years, molecular biology has revealed a superfamily of these phosphodiesterase isoenzymes. This book summarizes the present state of knowledge, as well as giving a comprehensive description of the compounds available. It will be invaluable for everyone who wants to choose the most suitable PDE inhibitor for their research or who is dealing with such drugs in a clinical setting.

ISBN: 9780122107207

Dimensions: unknown

Weight: 690g

228 pages