Calcium Regulation of Cellular Function
Shirish Shenolikar editor Angus C Nairn editor Paul Greengard editor Anthony R Means editor
Format:Hardback
Publisher:Elsevier Science Publishing Co Inc
Currently unavailable, and unfortunately no date known when it will be back
Volume 30 examines the prominent role of calcium as an intracellular second messenger. Leading investigators review a wide variety of studies on how calcium enters and moves through cells, how it interacts with its many binding proteins, and how calcium and its intracellular receptor, calmodulin, control vital cellular processes. Coverage includes a detailed analysis of the mechanisms by which calcium bound to calmodulin regulates contractile proteins in smooth muscle cells. Close attention is given to the roles of calcium and calmodulin-dependent protein kinases and phosphatases in synaptic signal transduction, protein synthesis, gene expression, programmed cell death, activation of T-lymphocytes, and control of cell division cycles. Other chapters discuss studies using genetically manipulable nonmammalian organisms to further proble the functions of calcium and calmodulin.
ISBN: 9780120361304
Dimensions: unknown
Weight: 730g
416 pages